Start: Rashee Rice, WR (Kansas City Chiefs)
The Eagles have yet to figure out their issues in the secondary this season as they have allowed the most receptions (154) and third-most yards (1,808) to opposing wide receivers. It makes starting the No. 1 wideout of Philly's opponent a go-to move every week and Rashee Rice is that player this week.
Rice has overtaken teammates like Kadarius Toney and Skyy Moore as Mahomes' favorite wideout to target this campaign. That was obvious in a Week 9 performance in which he took a designed screen to the house on the first drive and finished with the most snaps played of any Kansas City receiver.
It's worth noting at least 72 total points were put on the scoreboard in each of the last two head-to-head meetings between the Eagles and Chiefs. Seeing another high-scoring battle go down in front of a national audience would only increase the chances of Rice posting a top-15 WR Fantasy score.
Sit: Isaiah Pacheco, RB (Kansas City Chiefs)
Philadelphia's rush defense is absolutely filthy. It's a statement that has been proven right week after week as the Eagles lead the NFL in opponent rushing yards per game (66.3) and opponent rushing first downs per game (3.7). They have given up the fewest Fantasy points to opposing ball-carriers.
If it's not clear by now, running back Isaiah Pacheco's Week 11 outlook is far from bright. The Rutgers product draws a horrible matchup in the midst of what has been a rough stretch overall. Pacheco has averaged a subpar 3.8 yards per carry and tallied one touchdown in Kansas City's last four games.
Managers with depth on the roster should not hesitate to slide Pacheco out of the starting lineup and those stuck relying on him should temper expectations. His upside centers around whether or not he can find the end zone against one of the most disruptive defensive lines in the league on Monday.